工作职责:
A: The role of protein post-modification and stability via ubiquitin and deubiquitinase in pancreatic cancer.
B: Roles of deubiquitinase for stabilizing KLF4 in breast cancer after DNA damage.
1 Chen NH, et al. Proteostasis Modulators Sustain Missense VHL and Drive Tumorigenesis in Pancreatic cancer. To be submitted to Cell Reports
2 Chen NH, et al. Interplay between deubiquitinases USP46 stabilization and VHL ubiquitylation regulates KLF4 in Breast cancer
3 Chen NH, et al. Novel insight into Von Hippel-Lindau and its regulation in carcinogenesis and therapeutics. To be submitted to Cellular and Molecular Life Sciences
4 Chen NH, et al. Breast cancer stem cell and therapeutic implication.
5 Chen NH, et al. Protein microarray and its application
6 Chen NH, et al. Mechanisms, biology of proteasome deubiquitinases as novel targets for cancer therapy
7 Chen NH, et al. Impact of Posttranslational Modification in Pancreatic Carcinogenesis and Treatment